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Maintaining Metabolic Health Across the Life Course

Revealing the origins of cardiometabolic disease across the whole life course

Goals:​

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  • To understand the early life origin of cardiometabolic disease, leverage this knowledge to enhance postnatal care and improve future cardiovascular health.

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  • To establish the age-related mechanisms driving cardiovascular and neurodegenerative disease.

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  • To reveal the lifelong impact of the environment on cardiovascular disease development

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Projects and Research Groups

Management of type 2 diabetes in the elderly.

Life-style intervention.

Imaging steroid transport.

Ruth Andrew

​​How immune dysregulation in ageing promote cardiovascular diseases.

Bone marrow adipose tissue, diet, ageing, & sex differences in health & disease.

Utilising zebrafish and genetic screens to identify molecular mechanisms of adipose formation, distribution and function.

James Minchin

Chronic glucocorticoid therapy and cardiac/vascular remodelling across lifespan.

Mark Nixon

Epigenetics, development, and cell fate in cardiometabolic health and diseases.

Mechanisms linking development in utero to health and disease across the lifespan.

Rebecca Reynolds

Brown adipose tissue formation and function, including human studies and new imaging methods.

Roland Stimson

Pathological adipose remodelling with age and relationship to adipose function.

Robert Semple

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Institute for Neuroscience and Cardiovascular Research

Queen's Medical Research Institute,

Edinburgh BioQuarter,

Edinburgh EH16 4TJ

University of Edinburgh
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