Drivers Of Cardiometabolic Diseases

Understanding the Drivers Of Cardiometabolic Diseases

Understand how the immune, endocrine and nervous systems contribute to metabolic health.

Understand how dysregulation of these systems in obesity, diabetes and ageing contribute to the development of cardiometabolic diseases.

To leverage this knowledge for improved strategies to prevent and treat cardiometabolic diseases.

How steroid metabolism affects hormonal action in metabolic tissues.

Influence of 5alpha reductase inhibitors on cardiometabolic risk factors.

Ruth Andrew

Immune system, metabolism & obesity.

B cell contribution to metabolic deregualtion in obesity & ageing.

Macrophage & lipid transport.

RNA-binding proteins in metabolic and cardiovascular health.

Bone marrow adipose tissue, diet, ageing, & sex differences in health & disease.

Utilising zebrafish and genetic screens to identify molecular mechanisms of adipose formation, distribution and function.

James Minchin

Glucocorticoid induced insulin resistance and cardiac remodelling.

Obesity-induced vascular dysfunction.

Mark Nixon

Epigenetics, development, and cell fate in cardiometabolic health and diseases.

Brown adipose tissue formation and function, including human studies and new imaging methods.

Roland Stimson

The nature of insulin resistance and its role as a mediator of cardiometabolic and reproductive complications of obesity.

Robert Semple