University of EdinburghInstitute for Neuroscience and Cardiovascular Research

University of Edinburgh · INCR

Exploring Metabolism

Dive into our research at Edinburgh Metabolism. Discover how we strive to unravel the secrets of metabolic health throughout life.

Zebrafish lipid droplets and endothelial cells. Credit: James Minchin.
Adipose tissue imaging · James Minchin

Our Mission

Edinburgh Metabolism group photograph on outdoor steps

Edinburgh Metabolism, within the newly formed Institute for Neuroscience and Cardiovascular Research (INCR) at the University of Edinburgh, brings together basic and clinical scientists dedicated to understanding and improving metabolic health.

We focus on cutting-edge research to explore how metabolic processes support health, how they fail and lead to disease, and how novel approaches can reduce risk and improve treatments for metabolic disorders.

Advancing Cardiometabolic Health

Our work is centered on three key areas of research:

Mechanisms of Metabolic Health

We investigate the biological processes that maintain metabolic health across the lifespan. Understanding these mechanisms is critical for identifying ways to protect and promote metabolic function.

Disruptions in Metabolic Processes

Our research focuses on how these mechanisms go awry to contribute to conditions such as obesity, diabetes, fatty liver disease, cardiovascular diseases, and increased vulnerability to infections.

Innovative Approaches for Disease Prevention and Treatment

We are dedicated to developing novel strategies for reducing disease risk and improving treatment outcomes for established metabolic diseases, paving the way for better healthcare solutions.

Understanding The Drivers Of Cardiometabolic Diseases

Understanding The Drivers Of Cardiometabolic Diseases

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Genetic & Molecular Determinants Of Adipose Tissue Function

Genetic & Molecular Determinants Of Adipose Tissue Function

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Collaborations

We maintain close collaborations across the University of Edinburgh, particularly through the Edinburgh Diabetes Network, and with the Institute for Regeneration and Repair, the Institute of Genetics and Cancer, The Usher Institute, Edinburgh Neuroscience, and the Edinburgh Pregnancy Research Team. We benefit from a range of strong international collaborations, especially with Denmark (through the Danish Diabetes and Endocrine Academy, DDEA) and Malawi (through NIHR funding).

Our position in the Edinburgh BioQuarter campus seeds strong interactions with data scientists within the Usher Institute/DataLoch. Our wider outreach includes links with One Health programmes in the veterinary campus (e.g. LARIF) well as a strong interdisciplinary interface with physical science colleagues in the Kings Building Campus.

Events and meetings

In addition to INCR's wider seminar programme, Edinburgh Metabolism runs more thematically focused internal meetings, including a monthly Journal Club and a Steroid Interest Group. The UK-wide Adipose Tissue Discussion Group meetings in 2018, 2021 and 2023 were organised by our members. Our members also lead the Scottish Metabolomics Network.

Our Funders & Partners

We appreciate the invaluable support of our funders, whose contributions enable ground-breaking research and initiatives to advance metabolic health and improve outcomes for affected individuals.

WellcomeDiabetes UKNovoNordisk.JPGBritish Heart FoundationUKT1D Research Consortium.JPGChief Science OfficerUK Research and InnovationT1D Grand Challenge.JPGMedical Research ScotlandEdinburgh Lothians Health Foundation.JPGJDRF.JPGimage002.jpgHeart Research UKHelmsley.JPG

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